Experience with β-d-Glucan Assay for Diagnosis of Invasive Candidiasis in ICU Patients: Pilot Study from India
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چکیده
منابع مشابه
Early diagnosis of candidemia in intensive care unit patients with sepsis: a prospective comparison of (1→3)-β-D-glucan assay, Candida score, and colonization index
INTRODUCTION The culture-independent serum (1→3)-β-D-glucan (BG) detection test may allow early diagnosis of invasive fungal disease, but its clinical usefulness needs to be firmly established. A prospective single-center observational study was conducted to compare the diagnostic value of BG assay, Candida score (CS), and colonization index in intensive care unit (ICU) patients at risk for Can...
متن کاملIs (1→3)-β-D-glucan the missing link from bedside assessment to pre-emptive therapy of invasive candidiasis?
Invasive candidiasis is a frequent life-threatening complication in critically ill patients. Early diagnosis followed by prompt treatment aimed at improving outcome by minimizing unnecessary antifungal use remains a major challenge in the ICU setting. Timely patient selection thus plays a key role for clinically efficient and cost-effective management. Approaches combining clinical risk factors...
متن کاملLimitation of (1→3)-β-D-glucan monitoring in major elective surgery involving cardiopulmonary bypass
cated for detection of invasive candidiasis. Our data indicate that the rate o f false positive results is potentially high in some patient collectives of risk; for example, after cardiac artery bypass grafting (CABG). Th e recently published guidelines from the Surviving Sepsis Campaign recommend the use of (13)-β-dglucan as a surrogate for invasive candidiasis [1]. Fung al infections are inc...
متن کاملβ-D-glucan Surveillance with Preemptive Anidulafungin for Invasive Candidiasis in Intensive Care Unit Patients: A Randomized Pilot Study
BACKGROUND Invasive candidiasis (IC) is a devastating disease. While prompt antifungal therapy improves outcomes, empiric treatment based on the presence of fever has little clinical impact. Β-D-Glucan (BDG) is a fungal cell wall component detectable in the serum of patients with early invasive fungal infection (IFI). We evaluated the utility of BDG surveillance as a guide for preemptive antifu...
متن کاملمروری بر آسپرژیلوزیس تهاجمی در بیماران بستری شده در بخش مراقبت های ویژه با تاکید بر روش های تشخیصی
The genus Aspergillus is ubiquitous filamentous fungi with a wide distribution in nature. The species of Aspergillus are associated with a varied spectrum of diseases including allergy, superficial colonization and invasive infection in humans. Invasive aspergillosis (IA) is a serious and fulminate mycosis in immuno-deficient individuals. Over the last decade, IA has also been reported as a f...
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عنوان ژورنال:
دوره 4 شماره
صفحات -
تاریخ انتشار 2017